The place of sign language in science museums is an area of concern for deaf and hard of hearing visitors. Using gesture and visual communication, sign language allows special needs visitors access to science exhibits in different ways: through human mediation, multimedia interaction, films, interpretation, subtitles, closed caption, etc. We will discuss how to improve access of the deaf and hard of hearing public to museums by working with the Deaf National Associations in Europe. Creating new signs related to scientific concepts using the linguistic research of sign language is another avenue of exploration. The aim is to increase knowledge about deaf accessibility and understand sign language as a visual mode to easily convey complex ideas in science.