The Quai des Savoirs is a cultural establishment with no collection but a very large focus, dealing with science, research, innovation, and social issues - most of them raising inevitable controversies or deep questioning. But how can we encourage conversations not only among our public but also with the main protagonists? Can a cultural establishment be a starting point to open the dialogue around science and society? We took the decision some years ago, to dive into these huge and complex subjects (AI, critical mind, climate change, food, ...) by working specifically on imagery and emotions. The Art & Science field (creations, collaborations, exchanges, ...) is a way to work with our public but also with our partners (scientists, policy makers, artists, engaged people, ...). From our experience, programming art installations, organising art&science residencies but also designing a cultural season around an art-science exhibition can create a very fertile breeding ground and bring to the table various actors. In this session, we will share, reflect and exchange starting from a few case studies and experiences we had at Quai des Savoirs, including an original exhibition dealing with "Food tomorrow", created with 4 Science Fiction authors which was a starting point to build a participatory conversation on the possible directions of food production putting in contact the sometimes-contrasting opinions of decision makers, canteen staff, researchers as well as environmental associations.